The Sadequain Art Gallery, also known as Galerie Sadequain, was opened permanently to the public in 2011. It is named after the famous Pakistani artist Syed Sadequain Ahmed Naqvi and houses his works, including a ceiling mural begun in 1980s and dedicated to the citizens of Karachi, with one mural remaining incomplete after his death in 1987. The mural on the ceiling of the Frere Hall, Karachi displays in bold, the words, Arz-o-Samawat (Earth and the Heavens) and bears a historical significance, since it represents the last piece of work by Sadequain.
The gallery is now directly administered by the Karachi Municipal Corporation, and hosts several festivals.